In this Section
Issues: Health
Endocrine Disruption
An Overview and Resource List
Selected Bibliography on Endocrine Disruptors
Reviews
Colborn T, vom Saal FS, and Soto AM, Developmental Effects of Endocrine Disrupting Chemicals in Wildlife and Humans, Environ Health Persp, 101(5):378-384, 1993
Colborn T, The Wildlife/Human Connection: Modernizing Risk Decisions, Environ Health Persp, 102 (Suppl 12):55-59, 1994
Birnbaum LS, Endocrine Effects of Prenatal Exposure to PCBs, Dioxins, and Other Xenobiotics: Implications for Policy and Future Research, Environ Health Persp, 102:676-679, 1994
LeBlanc GA, Are Environmental Sentinels Signalling? Environ Health Persp, 103(10):888-890, 1995
Safe SH, Environmental and Dietary Estrogens and Human Health: Is There a Problem? Environ Health Persp, 103(4): 346-351, 1995
Semen Quality
Swan SH, Elkin EP, Fenster L, Have Sperm Densities Declined? A Reanalysis of Global Trend Data, Environ Hlth Persp, 105:1228-1232, 1997.
Auger J, Kunstmann JM, Czyglik F, and Jouannet P, Decline in Semen Quality Among Fertile Men in Paris During the Past 20 Years, NEJM, 332(5):281-285, 1995
Pajarinen J, Laippala P, Penttila A, and Karhunen PJ, Incidence of Disorders of Spermatogenesis in Middle Aged Finnish Men, 1981-91: Two Necropsy Series, Br Med J, 314:13-18, 1997
Fisch H, Goluboff ET, Olson JH, et al. Semen Analyses in 1,283 Men from the United States over a 25-Year Period: No Decline in Quality, Fertility and Sterility, 65(5):1009-1014, 1996
Testicular and Prostate Cancer
Toppari J, Larsen JC, Christiansen P, et al. Male Reproductive Health and Environmental Xenoestrogens, Environ Health Persp, 104 (Suppl 4): 741-803, 1996
Sakr WA, Haas GP, Cassin BF, et al. The Frequency of Carcinoma and Intraepithelial Neoplasia of the Prostate in Young Male Patients, J Urology, 150:379-385, 1993
Adami H-O, Bergstrom R, Mohner M, et al. Testicular Cancer in Nine Northern European Countries, Int J Cancer, 59: 33-38, 1994
Hypospadias and Cryptorchidism
Paulozzi LJ, Erickson JD, Jackson RJ, Hypospadias Trends in Two US Surveillance Systems, Pediatrics, 100(5):831-834, 1997
Giwercman A, Carlsen E, Keiding N, Skakkebaek NE, Evidence for Increasing Incidence of Abnormalities of the Human Testis: A Review, Environ Hlth Persp, 101 (Suppl 2):65-71, 1993
Breast Cancer
Wolff MS, Collman GW, Barrett JC, and Huff J, Breast Cancer and Environmental Risk Factors: Epidemiological and Experimental Findings, Annu Rev Pharmacol Toxicol, 36:573-596, 1996
Bradlow HL, Davis DL, Lin G, et al. Effects of Pesticides on the Ratio of 16(/2-Hydroxyestrone: A Biologic Marker of Breast Cancer Risk, Environ Health Persp, 103 (Suppl 7): 147-150, 1995
Davis DL, Axelrod D, Osborne MP, and Telang NT, Environmental Influences on Breast Cancer Risk, Science and Medicine, 4(3):56-63, 1997
Hunter DJ, Hankinson SE, Laden F, Colditz GA, et al. Plasma Organochlorine Levels and the Risk of Breast Cancer, NEJM, 337(18):1253-1258, 1997
Other Trends
Herman-Giddens ME, Slora EJ, Wasserman RC, et al., Secondary Sexual Characteristics and Menses in Young Girls Seen in Office Practice: A Study from the Pediatric Research in Office Settings Network, Pediatrics, 88(4):505-512, 1997
Davis DL, Gottleib MB, Stampnitzky JR, Reduced Ration of Male to Female Births in Several Industrial Countries, JAMA, 279:1018-1023, 1998
Dioxins and PCBs
Birnbaum L, Developmental Effects of Dioxins and Related Endocrine Disrupting Chemicals, Toxicol Lett, 82/83:743-750, 1995
Jacobson JL and Jacobson SW, Intellectual Impairment in Children Exposed to Polychlorinated Biphenyls in Utero, NEJM, 335:783-789, 1996
Bahn AK, Mills JL, Snyder PJ, et al, Hypothyroidism in Workers Exposed to Polybrominated Biphenyls, NEJM, 302(1):31-33, 1980
Koopman-Esseboom C, Morse DC, Weisglas-Kuperus N, et al, Effects of Dioxins and Polychlorinated Biphenyls on Thyroid Hormone Status of Pregnant Women and Their Infants, Ped Res, 36(4):468-473, 1994
Tilson HA, Jacobson JL, and Rogan WJ, Polychlorinated Biphenyls and the Developing Nervous System: Cross-Species Comparisons, Neurotox and Teratol, 12:239-248, 1990
Pesticides
Garry VF, Schreinemachers D, Harkins ME, and Griffith J, Pesticide Appliers, Biocides, and Birth Defects in Rural Minnesota, Environ Health Persp, 104:394-399, 1996
Morrison H, Savitz D, Semenciw R, et al. Farming and Prostate Cancer Mortality, Am J Epidemiol, 137(3): 270-280, 1993
Guillette LJ, Gross TS, Masson GR, et al. Developmental Abnormalities of the Gonad and Abnormal Sex Hormone Concentrations in Juvenile Alligators from Contaminated and Control Lakes in Florida, Environ Health Persp, 102:680-688, 1994
Plastics
Jaeger RJ and Rubin RJ, Migration of a Phthalate Ester Plasticizer from Polyvinyl Chloride Blood Bags into Stored Human Blood and its Localization in Human Tissues, NEJM, 287(22): 1114-1118, 1972
Feldman D and Krishnan A, Estrogens in Unexpected Places: Possible Implications for Researchers and Consumers, Environ Health Persp 103(Suppl 7): 129-133, 1995
Human Body Burdens
Lordo RA, Dinh KT, and Schwemberger JG, Semivolatile Organic Compounds in Adipose Tissue: Estimated Averages for the US Population and Selected Subpopulations, Am J Pub Health, 86:1253-1259, 1996
Rogan WJ, Gladen BC, McKinner JD, et al. Polychlorinated Biphenyls (PCBs) and Dichlorodiphenyl Dichloroethene (DDE) in Human Milk: Effects of Maternal Factors and Previous Lactation, Am J Pub Health, 76:172-177, 1986
Rogan WJ, Bagniewska MA, and Damstra T, Pollutants in Breast Milk, NEJM, 302(26):1450-1453, 1980
DES
Herbst AL, Ulfelder H, and Poskanzer DC, Adenocarcinoma of the Vagina: Association of Maternal Stilbestrol Therapy with Tumor Appearance in Young Women, NEJM, 284(16):878-881, 1971
Gill WB, Schumacher GFB, Bibbo M, et al. Association of Diethylstilbestrol Exposure in Utero With Cryptorchidism, Testicular Hypoplasia and Semen Abnormalities, J Urology, 122, 36-39, 1979
Wilcox AJ, Baird DD, Weinberg CR, et al. Fertility in Men Exposed Prenatally to Diethylstilbestrol, NEJM, 332:1411-1416, 1995
Mechanisms
Bergeron JM, Crews D, McLachlan JA, PCBs as Environmental Estrogens: Turtle Sex Determination as a Biomarker of Environmental Contamination, Environ Health Persp, 102:780-781, 1994
vom Saal FS, Timms, BG, Montano MM, et al., Prostate Enlargement in Mice Due to Fetal Exposure to Low Doses of Estradiol or Diethylstilbestrol and Opposite Effects at High Doses, Proc Natl Acad Sci, 94:2056-2061, 1997
Korach KS, McLachlan JA, Techniques for Detection of Estrogenicity, Environ Health Persp 103(Suppl 7):5-8, 1995
Sonnenschein C, Soto AM, Fernanzez MF, Olea N, et al. Development of a Marker of Estrogenic Exposure in Human Serum, Clin Chem, 41/12:1888-1895, 1995
Guillette LJ, Crain DA, Rooney AA, and Pickford DB, Organization Versus Activation: The Role of Endocrine-Disrupting Contaminants (EDCs) During Embryonic Development in Wildlife, Environ Health Persp 103(Suppl 7):157-164, 1995
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